RNA sequencing (RNA-Seq) is a powerful NGS tool with a variety of applications, including gene expression analysis, whole-transcriptome profiling, the identification of novel transcripts, the detection of coding variants, the detection of fusion genes, and the identification of alternative splicing, among others.
LEXOGEN – the RNA Experts offers:
1. NEW! Seamless RNAseq solutions for FFPE samples
Convenient workflows from FFPE sample extraction to data analysis:
SPLIT One-Step FFPE RNA Extraction and Lexogen FFPE Library Prep Kits offer a convenient end-to-end workflow for efficient processing of the most challenging FFPE material, including data analysis on Kangooroo – Lexogen’s intuitive web-based platform for NGS data processing. Read more
2. LUTHOR HD: Introducing High-Definition Single-Cell RNA Sequencing
- See more genes The technology behind LUTHOR HD enables exceptional sensitivity and allows access even to lowly expressed transcripts (< 10 copies/cell).
- Straightforward and fast No RNA extraction, mRNA enrichment, or ribosomal RNA depletion. Streamlined workflow takes you from RNA/ cell to ready library in only 6 hours.
- Ultra-low input, and “less-than-a-cell” input LUTHOR HD gives the best results with low initial inputs. Standard is 1 to 100 cells or 10 pg to 1 ng of total RNA, down to 0.15 pg is also possible!
- Simple data analysis Thanks to the innovative THOR technology, no more gDNA in your reads. This reduces bias, simplifies the data analysis and saves on read costs. Read more
3. Enhancing Plant Transcriptomics: Get the best sequencing results with convenient end-to-end RNA-Seq workflows
Unveiling the Hidden: Efficient rRNA Removal for Deeper Transcriptome Analysis. RiboCop ensures robust depletion of plant rRNA, ensuring a clear view of the remaining transcriptome.
RiboCop removes undesired cytoplasmic (5.8S, 18S and 25S), mitochondrial (5S, 18S and 26S) and plastid (4.5S, 5S, 16S and 23S) rRNA from intact as well as degraded input RNA. Ribodepletion thus affords an unbiased view of the transcriptome, including non-coding and non-polyadenylated transcripts. Read more
- Input 1 ng – 1 µg total RNA
- No enzymatic reactions or mechanical shearing
- Preserving full-length transcripts intact for downstream processing
End-to-end Workflow Solutions for Plant Transcriptomics:
Lexogen’s RiboCop kits seamlessly integrate with CORALL RNA-Seq library preparation kits. The full workflow can be completed in under 6 hours: from sample to sequencing-ready library in less than one day! Read more
4. Whole Transcriptome Library Prep Kits
The CORALL RNA-Seq Library Prep Kits enables fast and cost-efficient generation of stranded, UMI labelled, and unique dual indexed libraries for whole transcriptome analyses using Illumina® NGS platforms.
One for all and all-in-one. CORALL RNA-Seq is a well-established, fragmentation-free, and universal whole transcriptome RNA-Seq library prep which is completed in 6 steps (4.5 hours).
CORALL is the universal solution for all your samples offering exceptional performance on low input samples, down to 1 ng starting amount. It is the ideal solution for total RNA-Seq analysis on degraded and FFPE samples.
Watch a short video and learn more about CORALL:
New! Adjustable library size to perfectly fit your application: CORALL RNA-Seq V2 allows generation of longer libraries (~ 550 bp) for demanding applications such as alternative splicing, isoform analysis, and fusion detection.
5. Expression Profiling Library Prep Kits
QuantSeq is the gold-standard solution for gene expression studies targeting the 3’ end of RNA transcripts. The patented QuantSeq technology targets the 3’ ends of mRNA molecules, for a quick and cost-effective gene expression analysis by RNA-Seq, as well as other more advanced applications.
6. Meet the Family! RiboCop rRNA Depletion is Available for a Wide Variety of Species
RiboCop rRNA Depletion Kits are available for a wide range of species, including human, mouse, rat, bacteria (G+, G-, META), yeast and plants. The different RiboCop mixes can be easily combined for full flexibility and efficient simultaneous multi-species depletion. Read more
Read more about Lexogen’s RNAseq solutions on their website.
